Saturday, February 15, 2020

Should Human Embryonic Stem Cells be used in Scientific Research Essay

Should Human Embryonic Stem Cells be used in Scientific Research - Essay Example More than 20 years ago, scientists discovered how to derive stem cells from mouse embryos (NIH 2005), but more recently the potential for using human stem cells has been realized. The use of stem cells in medical research hinges on the fact that stem cells have the potential to differentiate into any of the cell types within the body in response to chemical signals. Theoretically they are able to divide limitlessly until they do become differentiated. Extensive research is being carried out in various parts of the world to determine the specific combination of chemical signals that will induce stem cells to differentiate into brain and nerve tissue as well as an array of organ tissue, including heart, pancreas, and liver. Stem cells are a potential source of an unlimited supply of replacement cells and tissues which can be used in treatments and cures for human diseases, as well as to explore the causes of diseases. For example, stem cells could be induced to differentiate into insulin-producing pancreatic cells which could be used to treat diabetes. This year, a team of researchers at Johns Hopkins University derived embryonic stem cells from mouse embryos, and transplanted these into paralyzed rats (JHMI, June 20, 2006). With the application of a surprisingly small number of cells, the paralysis was entirely cured, and the rats were able to walk again. It goes without saying that regenerating nerve tissue is a remarkable achievement. This research has the potential to be developed into treatments which could substantially increase the quality of life for millions of people suffering from a diverse range of illnesses. According to Douglas Kerr, the neurologist who led the research team, treatments b ased on this research could one day repair the damage done by Amyotrophic lateral sclerosis (Lou Gehrig's disease), multiple sclerosis, or traumatic spinal injury. With small adjustments, this approach could effectively treat Parkinson's disease and Huntington's disease. The human embryos used in the first successful attempts to isolate stem cells for laboratory use were derived from unneeded in vitro fertilization procedures (NIH 2005), and were used with the informed consent of the donor. However, as stem cell research has become more popular and the potential for it has been more fully realized, the need for consistent sources of cells has become more apparent, and this need has become a hotly-debated source of contention. In the United States, for example, there has been considerable debate over the past five years as to whether the government should fund research using frozen human embryos which are stored by in vitro fertilization clinics. Embryos used in such research would be approximately five days old (Associated Press, 2006) and would be destroyed in the research process. Opposition to the use of Human Embryonic Stem Cells on Religious Grounds Opposition of the use of human embryonic stem ce

Sunday, February 2, 2020

Ratio Analysis- discuss comparative risk Essay Example | Topics and Well Written Essays - 500 words

Ratio Analysis- discuss comparative risk - Essay Example It remains around 30 for all these years (except 2009) which is a good sign for the company. As far as interest risk ratio for 1-year gap is concerned, it is also stable (except 2009) around 32. It means that the company will not fear from its interest rate risk as it is not increasing consistently. The capital adequacy risk appears to be fair enough to cover unforeseen losses and obligations of the bank towards the investors. For the five years, the ratio is almost constant (except for 2010) which means that the risk for being unable to discharge its obligations is not increasing showing a positive sign for the company (Exhibit 4). Comparing the ratios of PNC limited with its peer group, it seems quite clear that the company’s performance is better than the peer group with respect to credit risk ratio, interest risk ratio (both 1-year and 3-year gap) and capital adequacy ratio. However, PNC requires working with its liquidity ratio to have an advantage over its peer group. PNC needs to improve its liquidity ratio to have complete advantage over its peer. For this purpose PNC will have to adopt some measures to recollect the amounts lent to those who appear to be bad debts. Further, the company needs to take steps to collect cash amounts in lieu of interest on loan expanded by it to customers. The company should also withdraw some of its less earning investments. Further, PNC should revise its policy for its current regular interest paying customers to urge them pay as soon as possible. All these steps will enable the company to increase its liquidity and hence will be able to avoid any liquidity risk arising in the near future